# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "HTGM" in publications use:' type: software license: GPL-2.0-or-later title: 'HTGM: High Throughput ''GoMiner''' version: '1.2' doi: 10.32614/CRAN.package.HTGM abstract: Two papers published in the early 2000's (Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) ) and (Zeeberg, B.R., Qin, H., Narashimhan, S., et al. (2005) ) implement 'GoMiner' and 'High Throughput GoMiner' ('HTGM') to map lists of genes to the Gene Ontology (GO) . Until recently, these were hosted on a server at The National Cancer Institute (NCI). In order to continue providing these services to the bio-medical community, I have developed stand-alone versions. The current package 'HTGM' builds upon my recent package 'GoMiner'. The output of 'GoMiner' is a heatmap showing the relationship of a single list of genes and the significant categories into which they map. 'High Throughput GoMiner' ('HTGM') integrates the results of the individual 'GoMiner' analyses. The output of 'HTGM' is a heatmap showing the relationship of the significant categories derived from each gene list. The heatmap has only 2 axes, so the identity of the genes are unfortunately "integrated out of the equation." Because the graphic for the heatmap is implemented in Scalable Vector Graphics (SVG) technology, it is relatively easy to hyperlink each picture element to the relevant list of genes. By clicking on the desired picture element, the user can recover the "lost" genes. authors: - family-names: Zeeberg given-names: Barry email: barryz2013@gmail.com repository: https://barryzee.r-universe.dev commit: e50e6dd91b3cd707fa2108f2f812110978bc829d date-released: '2025-05-14' contact: - family-names: Zeeberg given-names: Barry email: barryz2013@gmail.com