Package: HTGM2D Version: 1.1.1 Date: 2026-02-03 Title: Two Dimensional High Throughput 'GoMiner' Authors@R: c( person("Barry", "Zeeberg", email = "barryz2013@gmail.com", role = c("aut", "cre"))) Maintainer: Barry Zeeberg Author: Barry Zeeberg [aut, cre] Depends: R (>= 4.2.0) Imports: minimalistGODB, GoMiner, HTGM, grDevices, stats, gplots, jaccard, vprint, randomGODB, HGNChelper LazyData: true LazyDataCompression: xz Description: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process (BP), molecular function (MF) and cellular component (CC, i.e., subcellular localization). Tools such as 'GoMiner' (see Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) ) can leverage GO to perform ontological analysis of microarray and proteomics studies, typically generating a list of significant functional categories. Microarray studies are usually analyzed with BP, whereas proteomics researchers often prefer CC. To capture the benefit of both of those ontologies, I developed a two-dimensional version of 'High-Throughput GoMiner' ('HTGM2D'). I generate a 2D heat map whose axes are any two of BP, MF, or CC, and the value within a picture element of the heat map reflects the Jaccard metric p-value for the number of genes in common for the corresponding pair. License: GPL (>= 2) Encoding: UTF-8 VignetteBuilder: knitr Suggests: knitr, rmarkdown, testthat (>= 3.0.0) RoxygenNote: 7.3.3 Config/testthat/edition: 3 NeedsCompilation: no Packaged: 2026-06-20 09:17:51 UTC; root Config/pak/sysreqs: cmake make libicu-dev libuv1-dev zlib1g-dev Repository: https://barryzee.r-universe.dev Date/Publication: 2026-02-03 23:00:32 UTC RemoteUrl: https://github.com/cran/HTGM2D RemoteRef: HEAD RemoteSha: 860e4a7b390e81039f2b10b3a1595858d4764e9a