Package: HTGM4D Version: 1.0 Date: 2026-04-29 Title: Four Dimensional High Throughput 'GoMiner' Authors@R: c( person("Barry", "Zeeberg", email = "barryz2013@gmail.com", role = c("aut", "cre"))) Maintainer: Barry Zeeberg Author: Barry Zeeberg [aut, cre] Depends: R (>= 4.2.0) Imports: minimalistGODB, GoMiner, HTGM, HTGM2D, grDevices, stats, gplots, vprint, randomGODB, HGNChelper, png, magick, svglite, utils, graphics LazyData: true LazyDataCompression: xz Description: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process (BP), molecular function (MF) and cellular component (CC, i.e., subcellular localization). Tools such as 'GoMiner' (see Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) ) can leverage GO to perform ontological analysis of microarray and proteomics studies, typically generating a list of significant functional categories. Microarray studies are usually analyzed with BP, whereas proteomics researchers often prefer CC. To capture the benefit of both of those ontologies, I now present an enhancement of the existing two-dimensional version of 'High-Throughput GoMiner' ('HTGM2D'), which is called 'HTGM4D'. The original 'HTGM2D' is augmented by adding two instances of the original 'GoMiner' genes versus categories heatmaps, aligned with the categories axes of the 'HTGM2D' heatmap. License: GPL (>= 2) Encoding: UTF-8 VignetteBuilder: knitr Suggests: knitr, rmarkdown, testthat (>= 3.0.0) RoxygenNote: 7.3.3 Config/testthat/edition: 3 NeedsCompilation: no Packaged: 2026-07-02 08:12:26 UTC; root Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev libfribidi-dev make libharfbuzz-dev libmagick++-dev gsfonts libicu-dev libpng-dev libuv1-dev libssl-dev zlib1g-dev Repository: https://barryzee.r-universe.dev Date/Publication: 2026-05-02 11:11:05 UTC RemoteUrl: https://github.com/cran/HTGM4D RemoteRef: HEAD RemoteSha: 1dbb0905003c967fca3017bca79bbca9f51a5962